VITAL is a cohort study of the associations of supplement use with cancer risk.
In 2000–2002, eligible persons completed a 24-page questionnaire, including detailed questions about supplement use (duration, frequency, dose) during the previous 10 years from multivitamins and individual supplements/mixtures.
Lung cancer incidents through December 2005 were identified by linkage to the Surveillance, Epidemiology, and End Results cancer registry.
What did the researchers learn?
According to the researchers, “longer duration of use of individual β-carotene, retinol, and lutein supplements (but not total 10-year average dose) was associated with statistically significantly elevated risk of total lung cancer”.
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