Expert says Murdaugh’s pill habit is possible could lead to unprovoked outburst

Experts have revealed the devastating toll of opioid addiction after murder suspect Alex Murdaugh claimed to be a 60-pill-a-day addict.

Murdaugh – currently facing trial for the murder of his wife, Maggie, and son, Paul, in 2021 – said he initially got hooked on oxycodone after receiving the painkiller following surgery for a college football injury. 

The 54-year-old continued abusing the drugs for decades and he claims he was spending $60,000 per week on the opioid at the peak of his addiction. 

Many social media users raised doubts about whether someone could actually consume 60 pills a day and still function as a high-powered lawyer.

But Dr Tildabeth Doscher, an addiction medicine specialist at the University at Buffalo, told DailyMail.com: ‘Tolerance is more important than quantity’ when it comes to opioids. You or I would die if I took ten of those because my opioid receptors have no experience.’

Research shows that severe opioid addiction causes emotional swings, unprovoked outbursts, paranoia and depression, as well as crippling withdrawals. 

Paul, Alex, Maggie and Buster at a Gamecocks basketball game in January 2019. Murdaugh is accused of shooting Paul and Maggie dead on the night of June 7, 2021

‘It takes more and more and more to counter the withdrawal because once those opioid receptors are full, they start emptying out and cause withdrawal symptoms,’ Dr Doscher said.

‘People continue to use and use and use because they’re trying to avoid the pains of withdrawal.’

Opioid drugs work by binding to opioid receptors located in the brain, spinal cord and other regions of the body.

The drugs induce a feeling of euphoria and pleasure and can remove feelings of pain in a user.

These drugs are known to be addictive, as the body craves the euphoria they bring. 

Over time, the receptors lose sensitivity to the drug, though. This means that a person will require more opiates to reach that same feeling.

A person will slowly need more and more to reach that feeling, and the body can experience withdrawal symptoms if these cravings are unmet. 

Many people turn to more dangerous, street versions of the drug to get their fix once their addiction reaches a far enough point.

For Mr Murdaugh, a wealthy man who can allegedly afford to spend $60,000 daily on the pills, he was able to sustain this dangerous addiction for over a decade.

‘It just escalates and escalates,’ he told the court today. He said he visited a detox facility three times, the first in December 2017.

‘Opiate withdrawal is, whew, it’s hard,’ Murdaugh said. He described how ‘you throw up. You have terrible diarrhea. You sweat like you’re running a marathon. You can’t hold your legs still.’

Addiction of any kind is also linked to mental health disorders such as anxiety and depression. This is because the addiction can trigger feelings of sadness and hopelessness when a person can not get their fix. 

An addict is susceptible to losing control of their emotions and sometimes acting what others would deem as out of character. 

Spending large sums of money on the pills can also be stressful, as it drains resources from the rest of a person’s livelihood. This adds to the feelings of hopelessness. 

Paranoia is another common side-effect of addiction. Mr Murdaugh blamed the paranoia induced by his drug use for his inconsistent behavior in the wake of his wife and son’s murder. 

Dr Docher does not believe that Mr Murdaugh’s alleged violent crimes were caused by the opioids themselves, though.

She says that they are not the type of drugs that lead to these violent outbursts.

‘As far as violence goes, no. People will do things that they would have never done otherwise but murdering someone? No. It’s not like PCP or other drugs that make people more prone to violence,’ she explained.

’I’m never surprised to hear they took that and felt normal. I imagine when you take that much, you’re still trying to get the euphoria, the dissociative effects,’ Dr Doscher said.

‘So if he always takes 50 pills and then one day takes 70, he’s going to feel differently. There’s a stabilizing dose versus an excessive dose.’

Oxycodone is a highly addictive opioid used for long-term treatment of pain. It was first brought to the market in 2000

Dr Tildabeth Doscher, from the University of Buffalo, said that it is surely possible for a person to develop a tolerance to oxycodone where they can use more than 60 pills in one day

Mr Murdaugh use of opioids dates back to the early 2000s, where he was a member of the South Carolina Gamecocks college football team.

He was prescribed the drug by a doctor to help treat a knee injury. 

Oxycodone is a pain-relieving opioid sold under multiple brand names. While it has clinical uses, it is also known to be widely abused.

The drug is most commonly prescribed by doctors to relieve long-term pain in patients. 

It is usually taken as a capsule or tablet, and comes it regular and extended-release varieties. It can also be administered as an IV solution to patients in hospitals. 

The drug is detectable in a person’s system for up to three days, and has a half-life of three to six hours – which is the amount of time it takes the body to get rid of half of its prevalence in a person’s system.

It is easy to quickly build a dependency on the drug, though. Doctors say that those prescribed it should use it despite these risks, as the benefits outweigh the harms.

The family has been described as among the most evil in America for its role in the crisis has it facing dozens of lawsuits from individuals and local governments around the country.