Joe Biden has contracted Covid-19 and has started taking Pfizer’s antiviral pill to combat the disease, the White House announced.
The 79-year-old US president tested positive on Thursday morning, according to White House press secretary Karine Jean-Pierre, and will work from isolation until he tests negative. The White House said he is fully vaccinated with two additional booster shots and was experiencing “very mild symptoms”.
Jean-Pierre said in a statement: “Out of an abundance of transparency, the White House will provide a daily update on the president’s status as he continues to carry out the full duties of the office while in isolation.”
Kevin O’Connor, the president’s doctor, said in a letter that Biden was experiencing a runny nose, dry cough and fatigue.
He added: “The president has been fully vaccinated and twice-boosted, so I anticipate he will respond favourably, as most maximally protected patients do. Early use of [Pfizer’s drug] Paxlovid in this case provides additional protection against severe disease.”
The president was due to travel to Pennsylvania to make announcements on criminal justice and policing on Thursday but cancelled that trip as well as a planned weekend at his home in Wilmington, Delaware.
Shortly after the White House announced the diagnosis, Biden wrote on Twitter: “Folks, I’m doing great. Thanks for your concern.” The post said he had called politicians in Pennsylvania “to send my regrets for missing our event today” and that he was “keeping busy!”
A video of Biden was also published on his official Twitter account, in which he appeared standing on a balcony overlooking the White House lawn. “I’m doing well, getting a lot of work done, going to continue to get it done,” he said. “And in the meantime, thanks for your concern.”
Vice-president Kamala Harris’s office announced that she had tested negative for Covid-19. Jill Biden, the first lady, said the same on Twitter.
Biden came to office on a promise of regaining control of the pandemic, accusing his predecessor Donald Trump of having let the disease spread out of control.
But while the president has overseen a successful vaccine rollout, his efforts to quash the virus have been hampered by low take-up of jabs in some areas and new variants that have proved more infectious.
Since April, case numbers have risen in the US from about 28,000 new infections a day to 120,000. Deaths have remained steady, however, at around 400 a day.
On the campaign trail in 2020, officials described Biden as being very strict about ensuring those around him wore masks and did not come too close to him.
Paxlovid is available to those in the US who are experiencing mild to moderate symptoms and are at high risk of contracting severe disease. Biden has talked glowingly of its importance in helping control the spread of the virus, and his administration has allowed pharmacists to prescribe it in an effort to maximise its use.
There are signs, however, that some patients have suffered “rebound” effects once they stop taking the drug. This happened to Biden’s chief medical adviser Anthony Fauci, who said the symptoms were much worse when they returned days after he seemed to have cleared the disease.
Eric Topol, a cardiologist and the founder and director of the Scripps Research Translational Institute, said that Biden is at high risk for Covid because of his age but has no underlying conditions that would make him more vulnerable.
“They have given him Paxlovid quickly which may give him added protection, since he is at high risk for hospitalisation. They have pulled out all the stops,” he said. “He should do pretty well . . . but it’s never for sure.”
The Pfizer drug is given with ritonavir, an HIV medicine, which ensures the active ingredients stick around in the body for long enough to tackle the virus. But ritonavir cannot be taken with many common drugs, so Biden may need to stop taking some of his regular medication.
In his last medical, the US president’s doctor said he was prescribed the blood thinner Eliquis, the cholesterol treatment rosuvastatin and a nasal spray for allergic rhinitis.
The National Institutes of Health recommend patients taking Paxlovid reduce the dose of Eliquis, and said they may be advised to stop taking rosuvastatin for the duration of the treatment and for at least two to three days afterwards. He may also be advised to stop taking the nasal spray.
Topol said no medical problems would be caused by stopping taking these drugs temporarily, even if Biden were to need to take two courses of Paxlovid, over 10 days.
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